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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4245454e3ee7355912f8bc253b0af1d60f4dbd8301d6c810af5add28c207c044' 
  AND token = 'xoHUYv+i3itcB9z1zwFgCOmT4HyJBMxe0/rsl1lPCIE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}