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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b89d6f9d463fa67b3c9935f750241a1628dfa0a026af4409cd163fa83b6e21f' 
  AND token = 'nFd9qrLvVPBBiElIYg3rrdP6ieh/2LI7nTUykxHcjmA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}