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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f3fbda2bdeab957bcb6477dbf311045f4933c1e5f0a6c72069cee52e3eefa27' 
  AND token = 'wYruePB0iCD5lce88m5rjqTC6VpmP6BvFPzc5HMM7bo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}