SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '622a2321a6c1962b2a6c320dab30f60a27791bbb9a88bf0438dd60f78cf5ced2' 
  AND token = 'RHBAd83WyClygobFzKD3CovEFx/MF7IWokOJ7p9Y97s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}