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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ed22203b13d2f27098ad02baaa9add6e69d74b7cf4d35e9970d3ef20264cd23' 
  AND token = 'sPXiJlzbAfUXe6cpTPoyAmTzJtQOiY42iFWJKRk1E7E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}