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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cdb2c25f71925bf5e78983379c82644ab28fb77ce2f8ba22401e37a770f5a38b' 
  AND token = 'atpyfugjiYH/YopM2mvxkRtFwVA/4dmHWqraSLR5oJw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}