SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b25ff359a41cce283630d8614ee3947d3bd7e4ab87d5484a692a6064c0d2167a' 
  AND token = '7TP/3dktGoxmgoQvy+yZMW7sxkE+xHVxLLXM//248HQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}