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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b37a1df097213ffc3c44272feab7e0d52da5e5faae9444d48e89032c94b2368' 
  AND token = 'qfrnXjcpID67u9vSxyuwI8NHdYWU2++iZOih/Y9IbhU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}