SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da22932fb4d3c4e770389926151f5b684a51caf207d68d427df0b2f73fb929aa' 
  AND token = 'iod6FMwynBEWXFwA5/M51SXD+nvqSPXZq1kqdrz9s6E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}