SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d35a689c417bc30b3289a278df2d092590f02f06021aee2e30b53e12021d482' 
  AND token = 'fbC5/mT5Yuhst1tm/Jo6YRH0m6XHcn1WX5SmrU18wz0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}