SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8286ef7943dbcb4996b6b44a308880c9dfcb536524af8a1ec7ba32cb3d2f3648' 
  AND token = 'HaGVMMM9qVefTPlCXTJmfg9FhJ7m+Q4RSTMcJ1yCsOs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}