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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e4ad23e4f0aa0843bd5a927cdc0cb3511e5d539b12caa62ff300ed5e4d3db90' 
  AND token = 'yrLKhFMWz6Qlnag951p3/Bl/3bbsCdsra8ENfAgoNGI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}