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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14916475c993dd4782e9c596718935be62a05ea0c0ff48755da7b66743ec5110' 
  AND token = '+i4AGjzx1vCqUNxyr7lq2eJD5HAwbA8i92Q0WeUoKMs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}