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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1091dce89209d1d97baa2adbf7c027058c500abae1034dd1a1b99866e6190eb9' 
  AND token = 'meMd/6aQiQPY+EvtjfvO8TMSI5GqHW/8YkILlPxvbXo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}