SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3cb558f807d04ee7a19db40e23c0038833b4924bd65ca0872c485372a25807b' 
  AND token = 'kPz6gs5GVpHCTlOcITsQNBPMw1B7FL8ftQ1A/KojNJo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}