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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5aa81c7910a2df9404bc3661851c441b82bd7cf9b3d80ededbaefda3a4b253b' 
  AND token = 'cpvioiDZiQ7O+C3kJ1QurZb7CENp2cgwyZO1ulT4dhk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}