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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb114a3aa574677b9f7af54f90af98498fc06c865396dc48a261824814629ca8' 
  AND token = 'DFf8Wpo9bXlDepo+u57dVN5gNYnffmSlnFRTn6GgmWo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}