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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38cc7a56029c682c0ad32c2ede18846fc1a715e1b6619b8f9908510c82bf81c4' 
  AND token = 'gDQIEN85fRq1MT9s+TstXWJkGs05zNzoJsmzSDi46fs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}