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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '08072f3881cb0c9d02b6e85e3922bb91f7bc1c92eb24a9c1af382f240cbde468' 
  AND token = 'D3h1Qk+Kg8tJthng21N/cUa90Xkh6lm0yw5vhYsKCu8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}