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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '164cd2f4cc87092a9f561d8f53a08866022c107bab6408f22d4a37b6cdada1f9' 
  AND token = 'ar++b0QVyzJuCCZ1jKzqsr4Is0+Lud94aI+A8TIveN8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}