SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b3ff8a6d6026010789fb68b64af8a6efa72985759c08b92e248ae4cdb06675d' 
  AND token = 'SF3lfz3F35abHZUnqJboPqXNaVdGABJlwFDqXmAwua4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}