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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9191edeed8c3da95428699bfa0e680c05a16bbe7f4be5a86aabb1ab7a6196516' 
  AND token = 'QVN8Dj+Bs5/P9JJhtZMIf0jgJgTqjtUNZdOX9acDXVg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}