SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f26cc37479e288193b682dd8e55ea7ab0e356b5d2f0638b5bac7c86e69b1cf0' 
  AND token = 'X1HwyHtZZgvbiwNEVNHHsV8VCKaj3XBAdz5j8t4NWkk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}