SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f09f4c43493e6c354757f327ca1b168216e82940ef31ed7e9ebb8d6f961b5f0' 
  AND token = 'VFHnPBbeTr7oyQbqSqI0DkMZCyfCk5DPeJ7Ab+wE5wo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}