SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6d5eac620ba24be1f563bb5df839a308d23e55be8ef2636b30fbc5dbbb6e216' 
  AND token = 'O9WAN13cOofbEsY8uEwv+f1hof1LabbXAMk0OM2OQsc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}