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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '79be1fb1467df1cc9bc3aa6e144973ee09f50b072147cecfd78685e6f24f8eee' 
  AND token = 'LQ3Jbm+2MpPAagC7KUVlUKBR079DWr6IRDsCMzv1uPo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}