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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a36dc4228905de70d2632b780d52d6920621d708b04ff0209af85ce549c5da87' 
  AND token = 'EGR2kT1x965TwpJCmBjVNCGvNY98VRqWEkh+i2dHL6A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}