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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a18e68a3ae73d298e2d19c2f4ff2a3c5d0f10605cba2e79df9944b272ef283d3' 
  AND token = 'avEHeMGkO0HqZz+DfbHcNPAD2y/UKT/pV0PvFXy12Dw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}