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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '758353365456033671a11dd9e20b2a8682f3426f24e3896f29da12f06fa7c077' 
  AND token = 'uBJletoFMDRat4VQ7TdKpMNGCZG6tlXR4hIInY9ER6U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}