SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e3f7cab1026f0db4b4cc3e52720d88659f609ced2b4d59e99037fb2b3634857' 
  AND token = 'VA2F2IZVDMHNCQES0102ZJ76fmUrsLqt9kK0exCknEw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}