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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd8e5f1a72a3ceea56f46506ad38636e74827bab77cc2b60f85c3b8fec6fb287' 
  AND token = 'dv/dbY3zCps+8bkaHT4eANtgo7eVvE8qDG51lD+x3jM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}