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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6cecd757a7c7472cbc3638b7362203b0fb0a431c92a4e350d35348ec0c47e23e' 
  AND token = '2J2MJW5oRM7+YJVi/ppRkpzlPkzWqsnIxOvRDl6PREY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}