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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e5b1f2b835dfba97ec964eb4b378c8b369ce2f53d57550d7ea43b93dbe9501c' 
  AND token = 'Cegz3VlxecqoO6UlCkVWgpczSHdBeepaw+20D6sqtTg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}