SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '950d9de728e7a3842167e93702a1fdf8578b95c9c88507222d398d1fa8f1b74a' 
  AND token = 'TH2FTQ50yUZM7k+jAQ1kHEc2PFMFEiFliHIhqn/CwhQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}