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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f44e60fba4a0d0c7f87bc2901ffa695655e32649dc66f84a99066b604c7fa46' 
  AND token = '9kUqmn7lgaVZMzD6qhxQebRU6wXqNu6iw+BW3Yumk2Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}