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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26ac7ea25977c5915942b27f8dfa999297ca01f8f40f571f893c7f06594f453d' 
  AND token = 'UfScg9B4CIOUUSFKhq4UM2y42dDC1+o5sMY47+a6o0Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}