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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45da393c4ad53144db1bd5f50f365b06f02da06d1b3af4e926e25cd58975d576' 
  AND token = '6UmzA9jr4q9tvwEV6b1cLyQVphAtBQUqFtb/FTFQkXI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}