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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69fe1086cbc48c31c566c143777f56ad7999bbc7f7201cd2d2680c371f0f84c7' 
  AND token = 'Hb+Sk0RKMoLhAV0wkvFz9DTVF94md9dBzK4WFmb/Ctw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}