SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '286e404cd943a70c860d2eb9e8bd3908d734883f739d519e277363bc81168354' 
  AND token = 'qUPDBWOMFd3rxJzss2I4P1XsXB4a7qWSeM8Wjkn8Kfs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}