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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1767a2051be5052a997c0cb02f3f5da3105ad394f3453db52a96d7369dfb4def' 
  AND token = 'hDf1sLeotxe5aXsmfM3alu4isRVlRGO3jHRxLAXrC2E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}