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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01191c8cf28401798fe71f0041da3e626731ad1e09f92c1dce90118d3d443fa3' 
  AND token = 'pWt4iDhWgmRygNjbFnzmGY/NYRYkY8bw4UgKvrGc2po=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}