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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0435c2eb89eb2105b440a6fba02957cd0aada8fae93f8a606d60c5c9f3cf4bf9' 
  AND token = '6tHr813qY9mo1/GR3RfHL1NImDeRxRq7UYYL1YCwhaE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}