SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '582e16ce4a90140792bef6f6e3cf86939576a148a2406e3f96366b0189138545' 
  AND token = 'mV7kp5ucMinqzUd/xcPwlAhOuoEiUIvX5ebhZwewO8k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}