SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb03c8db39a00aab01d172ce3af6a226508875a0082a637f7ef804235fd27bde' 
  AND token = 'iLNOpB8Xy9JKkJ4CGsMIvZuSMp/ReyJcmRDDJI2Iy3A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}