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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c15738ca749b6eaabaee649ef5683c8514b4a1547249e7a9e177b6f9e22fab1' 
  AND token = '6GBWUoU9RRy9FfUCL+f5vasTxNieFRgvSsrKiTj7Eus=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}