SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43f9147df5661a745656f169513207703d6b00ab1715224b3329a33d63effe9b' 
  AND token = 'Ls+3MHNxb73O9CcNSQtgboebYsYY4LuwmtnVGfAca4Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}