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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '078268cda35896506c95dac59abd82c68718fcdff8f7bca086d1976982fe188d' 
  AND token = 'FvwzUmDI/h6p1Yt8yQ1kkwwec0a92xUUTY0wUBbGN60=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}