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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '645e676aecc9579a0a99258008fd4b7e3c371a75394d7783a3f79eab599742bd' 
  AND token = 'oBqP/1E5YeY3Dcd7FLe9jrM+bT49N1DdAK8QxtF/6Ec=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}