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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45b6f54abbc4bb8c532f1c5ecc97eb48f6a81eb261db3b16b605f3909380ac8f' 
  AND token = '4NxlDwRSDuZY/xtWjfMjAauuerLwn6oBxOyQmGlkX0A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}