SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1271a2c9af84751e730c3d95d833c9661e668bdaf43b2ad0ed929e536ee4f97' 
  AND token = '150CZUac4PmZKx3TDxpdpmnNx19cIZ+nUQ8LnZtggE0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}